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A Review of the Nonsurgical Treatment of Oral Leukoplakia
Joint Authors
Salles, Patrícia Ribeiro
da Silva, Tarcília Aparecida
de Mesquita, Ricardo Alves
Ribeiro, Adriana Spinola
Source
International Journal of Dentistry
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The aim of this paper was to assess the nonsurgical treatment of oral leukoplakia (OL).
A medline search from 1983 to 2009 was conducted.
The topical or systemic nonsurgical treatments or combination of both was reviewed.
The primary outcomes of interest were clinical resolution, malignant transformation, follow-up, and recurrence of OL.
Studies showed a rate higher than 50% of clinical resolution with photodynamic therapy, beta-carotene, lycopene, or vitamin A.
Few studies reported rates of recurrence from 5 to 67% and of malignant transformation from 8 to 23%.
There is a lack of randomized clinical trials that assess the effectiveness of nonsurgical treatment of OL.
At this time, randomized controlled trials for nonsurgical treatment of OL demonstrate no evidence of effective treatment in preventing malignant transformation and recurrence.
It reinforces that even after clinical resolution, OL should be regularly followed.
American Psychological Association (APA)
Ribeiro, Adriana Spinola& Salles, Patrícia Ribeiro& da Silva, Tarcília Aparecida& de Mesquita, Ricardo Alves. 2010. A Review of the Nonsurgical Treatment of Oral Leukoplakia. International Journal of Dentistry،Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-452841
Modern Language Association (MLA)
Ribeiro, Adriana Spinola…[et al.]. A Review of the Nonsurgical Treatment of Oral Leukoplakia. International Journal of Dentistry No. 2010 (2010), pp.1-10.
https://search.emarefa.net/detail/BIM-452841
American Medical Association (AMA)
Ribeiro, Adriana Spinola& Salles, Patrícia Ribeiro& da Silva, Tarcília Aparecida& de Mesquita, Ricardo Alves. A Review of the Nonsurgical Treatment of Oral Leukoplakia. International Journal of Dentistry. 2010. Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-452841
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-452841