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Very-Low-Density Lipoprotein : Complex Particles in Cardiac Energy Metabolism
Joint Authors
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The heart is a major consumer of energy and is able to utilise a wide range of substrates including lipids.
Nonesterified fatty acids (NEFA) were thought to be a favoured carbon source, but their quantitative contribution is limited because of their relative histotoxicity.
Circulating triacylglycerols (TAGs) in the form of chylomicrons (CMs) and very-low-density lipoprotein (VLDL) are an alternative source of fatty acids and are now believed to be important in cardiac metabolism.
However, few studies on cardiac utilisation of VLDL have been performed and the role of VLDL in cardiac energy metabolism remains unclear.
Hearts utilise VLDL to generate ATP, but the oxidation rate of VLDL-TAG is relatively low under physiological conditions; however, in certain pathological states switching of energy substrates occurs and VLDL may become a major energy source for hearts.
We review research regarding myocardial utilisation of VLDL and suggest possible roles of VLDL in cardiac energy metabolism: metabolic regulator and extracardiac energy storage for hearts.
American Psychological Association (APA)
Niu, You-Guo& Evans, Rhys D.. 2011. Very-Low-Density Lipoprotein : Complex Particles in Cardiac Energy Metabolism. Journal of Lipids،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-453124
Modern Language Association (MLA)
Niu, You-Guo& Evans, Rhys D.. Very-Low-Density Lipoprotein : Complex Particles in Cardiac Energy Metabolism. Journal of Lipids No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-453124
American Medical Association (AMA)
Niu, You-Guo& Evans, Rhys D.. Very-Low-Density Lipoprotein : Complex Particles in Cardiac Energy Metabolism. Journal of Lipids. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-453124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453124