Beneficial Effect of Conversion to Belatacept in Kidney-Transplant Patients with a Low Glomerular-Filtration Rate
Joint Authors
Esposito, Laure
Cardeau-Desangles, Isabelle
Rostaing, Lionel
Kamar, Nassim
Belliere, Julie
Del Bello, Arnaud
Capuani, Caroline
Guilbeau-Frugier, Céline
Source
Case Reports in Transplantation
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-18
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Belatacept has been found to be efficient at preserving good kidney function in maintenance kidney-transplant patients.
Herein, we report on the use of belatacept as a rescue therapy for two kidney-transplant patients presenting with severe adverse events after treatment with calcineurin inhibitors (CNIs) and mammalian target-of-rapamycin (mTOR) inhibitors.
Two kidney-transplant patients developed severely impaired kidney function after receiving CNIs.
The use of everolimus was associated with severe angioedema.
Belatacept was then successfully used to improve kidney function in both cases, even though estimated glomerular-filtration rate before conversion was <20 mL/min.
These case reports show that belatacept can be used as a rescue therapy, even if kidney function is very low in kidney-transplant patients who cannot tolerate CNIs and/or mTOR inhibitors.
American Psychological Association (APA)
Belliere, Julie& Guilbeau-Frugier, Céline& Del Bello, Arnaud& Esposito, Laure& Capuani, Caroline& Cardeau-Desangles, Isabelle…[et al.]. 2014. Beneficial Effect of Conversion to Belatacept in Kidney-Transplant Patients with a Low Glomerular-Filtration Rate. Case Reports in Transplantation،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-453161
Modern Language Association (MLA)
Belliere, Julie…[et al.]. Beneficial Effect of Conversion to Belatacept in Kidney-Transplant Patients with a Low Glomerular-Filtration Rate. Case Reports in Transplantation No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-453161
American Medical Association (AMA)
Belliere, Julie& Guilbeau-Frugier, Céline& Del Bello, Arnaud& Esposito, Laure& Capuani, Caroline& Cardeau-Desangles, Isabelle…[et al.]. Beneficial Effect of Conversion to Belatacept in Kidney-Transplant Patients with a Low Glomerular-Filtration Rate. Case Reports in Transplantation. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-453161
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453161