Marked Mydriasis and Neuritis Nervi Optici Associated with Galactorrhea Following Citalopram Treatment : A Case Report and Discussion

Abstract EN

We report the case of a 25-year-old women suffering from major depression who was treated with citalopram for several weeks with doses between 20 mg and 60 mg.

She gradually developed marked mydriasis within 2 months after treatment and subsequently neuritis nervi optici.

Moreover, abrupt galactorrhea occurred after 2 months of treatment.

All neuro-ophthalmological, neurophysiological, clinical laboratory, and neuroradiological diagnostic efforts did not reveal an underlying organic pathophysiology.

The ocular symptoms disappeared rapidly after the discontinuation of citalopram and pulse therapy with methyl-prednisolone.

However, galactorrhea persisted for a few weeks necessitating treatment with bromocriptine.