Low-Fat Nondairy Minidrink Containing Plant Stanol Ester Effectively Reduces LDL Cholesterol in Subjects with Mild to Moderate Hypercholesterolemia as Part of a Western Diet
Joint Authors
Hallikainen, Maarit
Gylling, Helena
Olsson, Johan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The cholesterol-lowering efficacy of plant stanol ester (STAEST) added to fat- or milk-based products is well documented.
However, their efficacy when added to nondairy liquid drinks is less certain.
Therefore, we have investigated the cholesterol-lowering efficacy of STAEST added to a soymilk-based minidrink in the hypercholesterolemic subjects.
In a randomized, double-blind, placebo-controlled parallel study, the intervention group (n=27) consumed 2.7 g/d of plant stanols as the ester in soymilk-based minidrink (65 mL/d) with the control group (n=29) receiving the same drink without added plant stanols once a day with a meal for 4 weeks.
Serum total, LDL, and non-HDL cholesterol concentrations were reduced by 8.0, 11.1, and 10.2% compared with controls (P<0.05 for all).
Serum plant sterol concentrations and their ratios to cholesterol declined by 12–25% from baseline in the STAEST group while the ratio of campesterol to cholesterol was increased by 10% in the controls (P<0.05 for all).
Serum precursors of cholesterol remained unchanged in both groups.
In conclusion, STAEST-containing soymilk-based low-fat minidrink consumed once a day with a meal lowered LDL and non-HDL cholesterol concentrations without evoking any side effects in subjects consuming normal Western diet.
The clinical trial registration number is NCT01716390.
American Psychological Association (APA)
Hallikainen, Maarit& Olsson, Johan& Gylling, Helena. 2013. Low-Fat Nondairy Minidrink Containing Plant Stanol Ester Effectively Reduces LDL Cholesterol in Subjects with Mild to Moderate Hypercholesterolemia as Part of a Western Diet. Cholesterol،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-453297
Modern Language Association (MLA)
Hallikainen, Maarit…[et al.]. Low-Fat Nondairy Minidrink Containing Plant Stanol Ester Effectively Reduces LDL Cholesterol in Subjects with Mild to Moderate Hypercholesterolemia as Part of a Western Diet. Cholesterol No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-453297
American Medical Association (AMA)
Hallikainen, Maarit& Olsson, Johan& Gylling, Helena. Low-Fat Nondairy Minidrink Containing Plant Stanol Ester Effectively Reduces LDL Cholesterol in Subjects with Mild to Moderate Hypercholesterolemia as Part of a Western Diet. Cholesterol. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-453297
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453297