Lessons from Cancer Immunoediting in Cutaneous Melanoma
Joint Authors
Aris, Mariana
Mordoh, José
Barrio, María Marcela
Source
Clinical and Developmental Immunology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-14
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
We will revisit the dual role of the immune system in controlling and enabling tumor progression, known as cancer immunoediting.
We will go through the different phases of this phenomenon, exposing the most relevant evidences obtained from experimental models and human clinical data, with special focus on Cutaneous Melanoma, an immunogenic tumor per excellence.
We will describe the different immunotherapeutic strategies employed and consider current models accounting for tumor heterogeneity.
And finally, we will propose a rational discussion of the progress made and the future challenges in the therapeutics of Cutaneous Melanoma, taking into consideration that tumor evolution is the resulting from a continuous feedback between tumor cells and their environment, and that different combinatorial therapeutic approaches can be implemented according to the tumor stage.
American Psychological Association (APA)
Aris, Mariana& Barrio, María Marcela& Mordoh, José. 2012. Lessons from Cancer Immunoediting in Cutaneous Melanoma. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-453344
Modern Language Association (MLA)
Aris, Mariana…[et al.]. Lessons from Cancer Immunoediting in Cutaneous Melanoma. Clinical and Developmental Immunology No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-453344
American Medical Association (AMA)
Aris, Mariana& Barrio, María Marcela& Mordoh, José. Lessons from Cancer Immunoediting in Cutaneous Melanoma. Clinical and Developmental Immunology. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-453344
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453344