Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma
Joint Authors
Pragal, Susanne
Schwarz, Andreas
Cecchi, Paolo Cipriano
Hanspeter, Esther
Biroli, Antonio
Source
Case Reports in Oncological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Brain metastases arise in 10%–40% of all cancer patients.
Up to one third of the patients do not have previous cancer history.
We report a case of a 67-years-old male patient who presented with confusion, tremor, and apraxia.
A brain MRI revealed an isolated right temporal lobe lesion.
A thorax-abdomen-pelvis CT scan showed no primary lesion.
The patient underwent a craniotomy with gross-total resection.
Histopathology revealed an intestinal-type adenocarcinoma.
A colonoscopy found no primary lesion, but a PET-CT scan showed elevated FDG uptake in the appendiceal nodule.
A right hemicolectomy was performed, and the specimen showed a moderately differentiated mucinous appendiceal adenocarcinoma.
Whole brain radiotherapy was administrated.
A subsequent thorax-abdomen CT scan revealed multiple lung and hepatic metastasis.
Seven months later, the patient died of disease progression.
In cases of undiagnosed primary lesions, patients present in better general condition, but overall survival does not change.
Eventual identification of the primary tumor does not affect survival.
PET/CT might be a helpful tool in detecting lesions of the appendiceal region.
To the best of our knowledge, such a case was never reported in the literature, and an appendiceal malignancy should be suspected in patients with brain metastasis from an undiagnosed primary tumor.
American Psychological Association (APA)
Biroli, Antonio& Cecchi, Paolo Cipriano& Pragal, Susanne& Hanspeter, Esther& Schwarz, Andreas. 2012. Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma. Case Reports in Oncological Medicine،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-453356
Modern Language Association (MLA)
Biroli, Antonio…[et al.]. Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma. Case Reports in Oncological Medicine No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-453356
American Medical Association (AMA)
Biroli, Antonio& Cecchi, Paolo Cipriano& Pragal, Susanne& Hanspeter, Esther& Schwarz, Andreas. Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma. Case Reports in Oncological Medicine. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-453356
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453356