Use of i-scan Endoscopic Image Enhancement Technology in Clinical Practice to Assist in Diagnostic and Therapeutic Endoscopy : A Case Series and Review of the Literature

Abstract EN

Background.

i-scan is a software-driven technology that allows modifications of sharpness, hue, and contrast to enhance mucosal imaging.

It uses postimage acquisition software with real-time mapping technology embedded in the endoscopic processor.

Aims.

To review applications of i-scan technology in clinical endoscopic practice.

Methods.

This is a case series of 20 consecutive patients who underwent endoscopic procedures where i-scan image enhancement algorithms were applied.

The main outcome measures were to compare mucosal lesions with high-definition white light endoscopy (HD-WLE) and i-scan image enhancement for the application of diagnostic sampling and therapy.

Results.

13 cases involving the upper GI tract and 7 cases of the lower GI tract are included.

For upper GI tract pathology i-scan assisted in diagnosis or therapy of Barrett’s esophagus with dysplasia, esophageal adenocarcinoma, HSV esophagitis, gastric MALT lymphoma, gastric antral intestinal metaplasia with dysplasia, duodenal follicular lymphoma, and a flat duodenal adenoma.

For lower GI tract pathology i-scan assisted in diagnosis or therapy of right-sided serrated adenomas, flat tubular adenoma, rectal adenocarcinoma, anal squamous cell cancer, solitary rectal ulcer, and radiation proctitis.

Conclusions.

i-scan imaging provides detailed topography of mucosal surfaces and delineates lesion edges, which can directly impact endoscopic management.