Partitioning of Cephalexin in Ionic Liquid Aqueous Two-Phase System Composed of 1-Butyl-3-Methylimidazolium Tetrafluoroborate and ZnSO4
Joint Authors
Yan, Yong Sheng
Ma, Jing Jing
Wang, Yun
Li, Yan Fang
Han, Juan
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Ionic liquid aqueous two-phase system (ILATPS) was applied in the extraction and separation of hydrosoluble antibiotics.
The partitioning behavior of cephalexin (CEX) in 1-butyl-3-methylimidazolium tetrafluoroborate ([Bmim]BF4)-ZnSO4 aqueous two-phase system was studied by the partitioning parameter of the extraction efficiency.
The effect of the volume of [Bmim]BF4, the concentration of ZnSO4, temperature, pH, and the volume of ZnSO4 solution was discussed concretely.
When the volume of [Bmim]BF4 was 2 mL and the concentration of ZnSO4 was 35%, the extraction efficiency of CEX could reach 92.64% with pH unadjusted.
The effect of the volume of [Bmim]BF4 on the extraction efficiency was higher than that of the concentration of ZnSO4.
The temperature influenced not only the formation of aqueous two-phase system but also the extraction efficiency of CEX.
The target was found to be preferentially extracted to the [Bmim]BF4-rich phase at the pH below 4.3.
The partition of CEX to the top phase was enhanced by increasing the volume of [Bmim]BF4, the concentration of ZnSO4, and temperature; however, the partition of CEX to the top phase increased by decreasing the pH.
American Psychological Association (APA)
Li, Yan Fang& Han, Juan& Wang, Yun& Ma, Jing Jing& Yan, Yong Sheng. 2012. Partitioning of Cephalexin in Ionic Liquid Aqueous Two-Phase System Composed of 1-Butyl-3-Methylimidazolium Tetrafluoroborate and ZnSO4. Journal of Chemistry،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-453438
Modern Language Association (MLA)
Li, Yan Fang…[et al.]. Partitioning of Cephalexin in Ionic Liquid Aqueous Two-Phase System Composed of 1-Butyl-3-Methylimidazolium Tetrafluoroborate and ZnSO4. Journal of Chemistry No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-453438
American Medical Association (AMA)
Li, Yan Fang& Han, Juan& Wang, Yun& Ma, Jing Jing& Yan, Yong Sheng. Partitioning of Cephalexin in Ionic Liquid Aqueous Two-Phase System Composed of 1-Butyl-3-Methylimidazolium Tetrafluoroborate and ZnSO4. Journal of Chemistry. 2012. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-453438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453438