Autotaxin : Its Role in Biology of Melanoma Cells and as a Pharmacological Target

Author

Jankowski, Maciej

Source

Enzyme Research

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-03-08

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Biology

Abstract EN

Autotaxin (ATX) is an extracellular lysophospholipase D (lysoPLD) released from normal cells and cancer cells.

Activity of ATX is detected in various biological fluids.

The lysophosphatidic acid (LPA) is the main product of ATX.

LPA acting through specific G protein-coupled receptors (LPA1-LPA6) affects immunological response, normal development, and malignant tumors' formation and progression.

In this review, the impact of autotoxin on biology of melanoma cells and potential treatment is discussed.

American Psychological Association (APA)

Jankowski, Maciej. 2011. Autotaxin : Its Role in Biology of Melanoma Cells and as a Pharmacological Target. Enzyme Research،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-453554

Modern Language Association (MLA)

Jankowski, Maciej. Autotaxin : Its Role in Biology of Melanoma Cells and as a Pharmacological Target. Enzyme Research No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-453554

American Medical Association (AMA)

Jankowski, Maciej. Autotaxin : Its Role in Biology of Melanoma Cells and as a Pharmacological Target. Enzyme Research. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-453554

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-453554