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Natural History of Temporal Lobe Epilepsy : Antecedents and Progression
Joint Authors
Shukla, Garima
Prasad, Asuri N.
Source
Epilepsy Research and Treatment
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Temporal lobe epilepsy represents the largest group of patients with treatment resistant/medically intractable epilepsy undergoing epilepsy surgery.
The underpinnings of common forms of TLE in many instances begin in early life with the occurrence of an initial precipitating event.
The first epileptic seizure often occurs after a variable latency period following this event.
The precise natural history and progression following the first seizure to the development of TLE, its subsequent resolution through spontaneous remission or the development of treatment resistant epilepsy remain poorly understood.
Our present understanding of the role played by these initial events, the subsequent latency to development of temporal lobe epilepsy, and the emergence of treatment resistance remains incomplete.
A critical analysis of published data suggest that TLE is a heterogeneous condition, where the age of onset, presence or absence of a lesion on neuroimaging, the initial precipitating event, association with febrile seizures, febrile status epilepticus, and neurotropic viral infections influence the natural history and outcome.
The pathways and processes through which these variables coalesce into a framework will provide the basis for an understanding of the natural history of TLE.
The questions raised need to be addressed in future prospective and longitudinal observational studies.
American Psychological Association (APA)
Shukla, Garima& Prasad, Asuri N.. 2012. Natural History of Temporal Lobe Epilepsy : Antecedents and Progression. Epilepsy Research and Treatment،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-453574
Modern Language Association (MLA)
Shukla, Garima& Prasad, Asuri N.. Natural History of Temporal Lobe Epilepsy : Antecedents and Progression. Epilepsy Research and Treatment No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-453574
American Medical Association (AMA)
Shukla, Garima& Prasad, Asuri N.. Natural History of Temporal Lobe Epilepsy : Antecedents and Progression. Epilepsy Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-453574
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453574