Application of Symmetry Adapted Function Method for Three-Dimensional Reconstruction of Octahedral Biological Macromolecules
Joint Authors
Yang, Qibin
Zeng, Songjun
Liu, Hongrong
Source
International Journal of Biomedical Imaging
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-01-21
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
A method for three-dimensional (3D) reconstruction of macromolecule assembles, that is, octahedral symmetrical adapted functions (OSAFs) method, was introduced in this paper and a series of formulations for reconstruction by OSAF method were derived.
To verify the feasibility and advantages of the method, two octahedral symmetrical macromolecules, that is, heat shock protein Degp24 and the Red-cell L Ferritin, were utilized as examples to implement reconstruction by the OSAF method.
The schedule for simulation was designed as follows: 2000 random orientated projections of single particles with predefined Euler angles and centers of origins were generated, then different levels of noises that is signal-to-noise ratio (S/N) =0.1,0.5, and 0.8 were added.
The structures reconstructed by the OSAF method were in good agreement with the standard models and the relative errors of the structures reconstructed by the OSAF method to standard structures were very little even for high level noise.
The facts mentioned above account for that the OSAF method is feasible and efficient approach to reconstruct structures of macromolecules and have ability to suppress the influence of noise.
American Psychological Association (APA)
Zeng, Songjun& Liu, Hongrong& Yang, Qibin. 2010. Application of Symmetry Adapted Function Method for Three-Dimensional Reconstruction of Octahedral Biological Macromolecules. International Journal of Biomedical Imaging،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-453591
Modern Language Association (MLA)
Zeng, Songjun…[et al.]. Application of Symmetry Adapted Function Method for Three-Dimensional Reconstruction of Octahedral Biological Macromolecules. International Journal of Biomedical Imaging No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-453591
American Medical Association (AMA)
Zeng, Songjun& Liu, Hongrong& Yang, Qibin. Application of Symmetry Adapted Function Method for Three-Dimensional Reconstruction of Octahedral Biological Macromolecules. International Journal of Biomedical Imaging. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-453591
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453591