Accuracy of Diagnostic Biopsy for Cutaneous Melanoma : Implications for Surgical Oncologists
Joint Authors
Hernández-Irizarry, Roberto
Hieken, Tina J.
Boll, Julia M.
Jones Coleman, Jamie E.
Source
International Journal of Surgical Oncology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and Objectives.
While excisional biopsy is recommended to diagnose cutaneous melanoma, various biopsy techniques are used in practice.
We undertook this study to identify how frequently final tumor stage and treatment recommendations changed from diagnostic biopsy to final histopathology after wide local excision (WLE).
Methods.
We compared the histopathology of the dermatopathologist-reviewed diagnostic biopsy and final WLE in 332 cutaneous melanoma patients.
Results.
Tumor sites were extremity (51%), trunk (33%), and head/neck (16%).
Initial biopsy types were excisional (56%), punch (21%), shave (18%), and incisional (5%).
Most diagnostic biopsies were margin positive regardless of technique, and 36% of patients had residual melanoma on WLE.
T-stage changed in 8% of patients, of whom 59% were diagnosed by punch biopsy, 15% by incisional biopsy, 15% by shave biopsy, and 11% by excisional biopsy (P<0.0001).
Treatment recommendations changed in 6%: 2% after excisional biopsy, 5% after shave biopsy, 18% after punch biopsy, and 18% after incisional biopsy (P<0.0001).
Conclusions.
Although most biopsy margins were positive, T-stage and treatment changed for only a minority of melanoma patients.
Our data provide valuable information to inform patient discussion regarding the likelihood of a change in prognosis and the need for secondary procedures after WLE.
These data support the superiority of dermatopathologist-reviewed excisional biopsy when feasible.
American Psychological Association (APA)
Hieken, Tina J.& Hernández-Irizarry, Roberto& Boll, Julia M.& Jones Coleman, Jamie E.. 2013. Accuracy of Diagnostic Biopsy for Cutaneous Melanoma : Implications for Surgical Oncologists. International Journal of Surgical Oncology،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-453704
Modern Language Association (MLA)
Hieken, Tina J.…[et al.]. Accuracy of Diagnostic Biopsy for Cutaneous Melanoma : Implications for Surgical Oncologists. International Journal of Surgical Oncology No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-453704
American Medical Association (AMA)
Hieken, Tina J.& Hernández-Irizarry, Roberto& Boll, Julia M.& Jones Coleman, Jamie E.. Accuracy of Diagnostic Biopsy for Cutaneous Melanoma : Implications for Surgical Oncologists. International Journal of Surgical Oncology. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-453704
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453704