The Effect of an Enamel Matrix Derivative (Emdogain) Combined with Bone Ceramic on Bone Formation in Mandibular Defects : A Histomorphometric and Immunohistochemical Study in the Canine
Joint Authors
Shah Abouei, Mohammad
Soolari, Ahmad
Mohammad Razavi, Sayed
Zia, Peyaman
Birang, Reza
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Background.
The purpose of this study was to evaluate the combination of an enamel matrix derivative (EMD) and an osteoconductive bone ceramic (BC) in improving bone regeneration.
Materials and Methods.
Four cylindrical cavities (6×6 mm) were prepared bilaterally in the mandible in three dogs.
The defects were randomly assigned to four different treatments—filled with EMD/BC and covered with a nonresorbable membrane, filled with EMD/BC without membrane, membrane coverage only, or control (left untreated)—and healed for 2, 4, or 6 weeks.
Harvested specimens were prepared for histologic, histomorphometric, and immunohistochemical analyses.
Results.
Sites treated with EMD/BC with or without membrane showed more total bone formation and lamellar bone formation than membrane-only and control defects.
There were no statistically significant differences in total bone formation between EMD/BC with or without membrane.
Conclusion.
EMD with BC might improve bone formation in osseous defects more than membrane coverage alone; the use of a membrane had no significant additive effect on total bone formation.
American Psychological Association (APA)
Birang, Reza& Shah Abouei, Mohammad& Mohammad Razavi, Sayed& Zia, Peyaman& Soolari, Ahmad. 2012. The Effect of an Enamel Matrix Derivative (Emdogain) Combined with Bone Ceramic on Bone Formation in Mandibular Defects : A Histomorphometric and Immunohistochemical Study in the Canine. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-453730
Modern Language Association (MLA)
Birang, Reza…[et al.]. The Effect of an Enamel Matrix Derivative (Emdogain) Combined with Bone Ceramic on Bone Formation in Mandibular Defects : A Histomorphometric and Immunohistochemical Study in the Canine. The Scientific World Journal No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-453730
American Medical Association (AMA)
Birang, Reza& Shah Abouei, Mohammad& Mohammad Razavi, Sayed& Zia, Peyaman& Soolari, Ahmad. The Effect of an Enamel Matrix Derivative (Emdogain) Combined with Bone Ceramic on Bone Formation in Mandibular Defects : A Histomorphometric and Immunohistochemical Study in the Canine. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-453730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453730