Antiepidermal Growth Factor Receptor Monoclonal Antibodies : Applications in Colorectal Cancer
Joint Authors
Kozuch, Peter S.
Kittai, Adam
Azizi, Efat
Source
Chemotherapy Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-08
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Patients with metastatic colorectal cancer have a poor prognosis and present a challenge to clinicians.
The role of the antiepidermal growth factor receptor (EGFR) pathway in tumorogenesis and tumor progression has been well defined.
This paper will review the use of anti-EGFR monoclonal antibodies in the treatment of operable, as well as metastatic colorectal cancer both in the setting of KRAS mutation unselected patients and later in KRAS wild-type patients.
Active investigations designed to further identify predictive biomarkers that may be potentially druggable are reviewed as well.
American Psychological Association (APA)
Azizi, Efat& Kittai, Adam& Kozuch, Peter S.. 2012. Antiepidermal Growth Factor Receptor Monoclonal Antibodies : Applications in Colorectal Cancer. Chemotherapy Research and Practice،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-453858
Modern Language Association (MLA)
Azizi, Efat…[et al.]. Antiepidermal Growth Factor Receptor Monoclonal Antibodies : Applications in Colorectal Cancer. Chemotherapy Research and Practice No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-453858
American Medical Association (AMA)
Azizi, Efat& Kittai, Adam& Kozuch, Peter S.. Antiepidermal Growth Factor Receptor Monoclonal Antibodies : Applications in Colorectal Cancer. Chemotherapy Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-453858
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453858