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Myeloid Cells in the Tumor Microenvironment : Modulation of Tumor Angiogenesis and Tumor Inflammation
Joint Authors
Varner, Judith A.
Schmid, Michael C.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-16
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Myeloid cells are a heterogeneous population of bone marrow-derived cells that play a critical role during growth and metastasis of malignant tumors.
Tumors exhibit significant myeloid cell infiltrates, which are actively recruited to the tumor microenvironment.
Myeloid cells promote tumor growth by stimulating tumor angiogenesis, suppressing tumor immunity, and promoting metastasis to distinct sites.
In this review, we discuss the role of myeloid cells in promoting tumor angiogenesis.
Furthermore, we describe a subset of myeloid cells with immunosuppressive activity (known as myeloid-derived suppressor cells).
Finally, we will comment on the mechanisms regulating myeloid cell recruitment to the tumor microenvironment and on the potential of myeloid cells as new targets for cancer therapy.
American Psychological Association (APA)
Schmid, Michael C.& Varner, Judith A.. 2010. Myeloid Cells in the Tumor Microenvironment : Modulation of Tumor Angiogenesis and Tumor Inflammation. Journal of Oncology،Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-453950
Modern Language Association (MLA)
Schmid, Michael C.& Varner, Judith A.. Myeloid Cells in the Tumor Microenvironment : Modulation of Tumor Angiogenesis and Tumor Inflammation. Journal of Oncology No. 2010 (2010), pp.1-10.
https://search.emarefa.net/detail/BIM-453950
American Medical Association (AMA)
Schmid, Michael C.& Varner, Judith A.. Myeloid Cells in the Tumor Microenvironment : Modulation of Tumor Angiogenesis and Tumor Inflammation. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-453950
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453950