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Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients : Effects of Antiretroviral Therapy and Adipose Tissue Distribution
Joint Authors
van Wijk, Jeroen P. H.
Cabezas, Manuel Castro
Source
International Journal of Vascular Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-22
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The use of combination antiretroviral therapy (CART) in HIV-infected patients has resulted in a dramatic decline in AIDS-related mortality.
However, mortality due to non-AIDS conditions, particularly cardiovascular disease (CVD) seems to increase in this population.
CART has been associated with several metabolic risk factors, including insulin resistance, low HDL-cholesterol, hypertriglyceridemia and postprandial hyperlipidemia.
In addition, HIV itself, as well as specific antiretroviral agents, may further increase cardiovascular risk by interfering with endothelial function.
As the HIV population is aging, CVD may become an increasingly growing health problem in the future.
Therefore, early diagnosis and treatment of cardiovascular risk factors is warranted in this population.
This paper reviews the contribution of both, HIV infection and CART, to insulin resistance, postprandial hyperlipidemia and cardiovascular risk in HIV-infected patients.
Strategies to reduce cardiovascular risk are also discussed.
American Psychological Association (APA)
van Wijk, Jeroen P. H.& Cabezas, Manuel Castro. 2011. Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients : Effects of Antiretroviral Therapy and Adipose Tissue Distribution. International Journal of Vascular Medicine،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-453951
Modern Language Association (MLA)
van Wijk, Jeroen P. H.& Cabezas, Manuel Castro. Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients : Effects of Antiretroviral Therapy and Adipose Tissue Distribution. International Journal of Vascular Medicine No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-453951
American Medical Association (AMA)
van Wijk, Jeroen P. H.& Cabezas, Manuel Castro. Hypertriglyceridemia, Metabolic Syndrome, and Cardiovascular Disease in HIV-Infected Patients : Effects of Antiretroviral Therapy and Adipose Tissue Distribution. International Journal of Vascular Medicine. 2011. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-453951
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453951