Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus
Joint Authors
Yagi, Hideo
Kawamata, Toshio
Ishii, Mitsuaki
Akiguchi, Ichiro
Watanabe, Toshiyuki
Watanabe, Yuko
Mashimo, Hideaki
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We aimed to investigate the characteristics of Parkinsonian features assessed by the unified Parkinson's disease rating scale (UPDRS) and determine their correlations with the computed tomography (CT) findings in patients with idiopathic normal pressure hydrocephalus (iNPH).
The total score and the scores for arising from chair, gait, postural stability, and body hypokinesia in the motor examination section of UPDRS were significantly improved after shunt operations.
Stepwise multiple regression analysis revealed that postural stability was the determinant of the gait domain score of the iNPH grading scale.
The canonical correlation analysis between the CT findings and the shunt-responsive Parkinsonian features indicated that Evans index rather than midbrain diameters had a large influence on the postural stability.
Thus, the pathophysiology of postural instability as a cardinal feature of gait disturbance may be associated with impaired frontal projections close to the frontal horns of the lateral ventricles in the iNPH patients.
American Psychological Association (APA)
Ishii, Mitsuaki& Kawamata, Toshio& Akiguchi, Ichiro& Yagi, Hideo& Watanabe, Yuko& Watanabe, Toshiyuki…[et al.]. 2010. Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-453956
Modern Language Association (MLA)
Ishii, Mitsuaki…[et al.]. Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-453956
American Medical Association (AMA)
Ishii, Mitsuaki& Kawamata, Toshio& Akiguchi, Ichiro& Yagi, Hideo& Watanabe, Yuko& Watanabe, Toshiyuki…[et al.]. Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-453956
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-453956