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Preoperative Comorbidity Correlates Inversely with Survival after Intestinal and Multivisceral Transplantation in Adults
Joint Authors
Tzakis, Andreas G.
Middleton, Stephen J.
Butler, Andrew J.
Pither, Charlotte
Gabe, Simon M.
Island, Eddie R.
Nishida, Seigo
Jamieson, Neville V.
Dawwas, Muhammad
Moon, Jung
Hidenori, Takahashi
Sivaprakasam, Rajesh
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We investigated the relationship between preoperative comorbidity and postoperative survival after intestinal transplantation.
Each patient received a score for preoperative comorbidity.
Each comorbidity was given a score based on the degree it impaired function (score range 0–3).
A total score was derived from the summation of individual comorbidity scores.
Patients (72 adults (M : F, 33 : 39)) received an isolated intestinal graft (27) or a cluster graft (45).
Mean (standard deviation) survival was 1501 (1444) days.
The Kaplan-Meier analysis revealed a significant inverse association between survival and comorbidity score (logrank test for trend, P<0.0001).
Patients grouped into comorbidity scores of 0 and 1, 2 and 3, 4 and 5, 6, and above had hazard ratios (95% confidence intervals) for death (compared to group 0 + 1), which increased with comorbidity scores: 1.945 (0.7622–5.816), 5.075 (3.314–36.17), and 13.77 (463.3–120100), respectively, (P<0.0001).
Receiver-operator curves at 1, 3, 5, and 10 years postoperative had “C” statistics of 0.88, 0.85, 0.88, and 0.92, respectively.
When evaluating patients for transplantation, the degree of comorbidity should be considered as a major factor influencing postoperative survival.
American Psychological Association (APA)
Sivaprakasam, Rajesh& Hidenori, Takahashi& Pither, Charlotte& Nishida, Seigo& Butler, Andrew J.& Island, Eddie R.…[et al.]. 2013. Preoperative Comorbidity Correlates Inversely with Survival after Intestinal and Multivisceral Transplantation in Adults. Journal of Transplantation،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-454078
Modern Language Association (MLA)
Sivaprakasam, Rajesh…[et al.]. Preoperative Comorbidity Correlates Inversely with Survival after Intestinal and Multivisceral Transplantation in Adults. Journal of Transplantation No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-454078
American Medical Association (AMA)
Sivaprakasam, Rajesh& Hidenori, Takahashi& Pither, Charlotte& Nishida, Seigo& Butler, Andrew J.& Island, Eddie R.…[et al.]. Preoperative Comorbidity Correlates Inversely with Survival after Intestinal and Multivisceral Transplantation in Adults. Journal of Transplantation. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-454078
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454078