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Molecular Imaging : A Promising Tool to Monitor Islet Transplantation
Joint Authors
Moore, Anna
Wang, Ping
Medarova, Zdravka
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-15
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Replacement of insulin production by pancreatic islet transplantation has great potential as a therapy for type 1 diabetes mellitus.
At present, the lack of an effective approach to islet grafts assessment limits the success of this treatment.
The development of molecular imaging techniques has the potential to fulfill the goal of real-time noninvasive monitoring of the functional status and viability of the islet grafts.
We review the application of a variety of imaging modalities for detecting endogenous and transplanted beta-cell mass.
The review also explores the various molecular imaging strategies for assessing islet delivery, the metabolic effects on the islet grafts as well as detection of immunorejection.
Here, we highlight the use of combined imaging and therapeutic interventions in islet transplantation and the in vivo monitoring of stem cells differentiation into insulin-producing cells.
American Psychological Association (APA)
Wang, Ping& Medarova, Zdravka& Moore, Anna. 2011. Molecular Imaging : A Promising Tool to Monitor Islet Transplantation. Journal of Transplantation،Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-454113
Modern Language Association (MLA)
Wang, Ping…[et al.]. Molecular Imaging : A Promising Tool to Monitor Islet Transplantation. Journal of Transplantation No. 2011 (2011), pp.1-14.
https://search.emarefa.net/detail/BIM-454113
American Medical Association (AMA)
Wang, Ping& Medarova, Zdravka& Moore, Anna. Molecular Imaging : A Promising Tool to Monitor Islet Transplantation. Journal of Transplantation. 2011. Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-454113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454113