Impact of Standardized Allergen-Removed Rhus verniciflua Stokes Extract on Advanced Adenocarcinoma of the Ampulla of Vater : A Case Series
Joint Authors
Kwon, Eunmi
Lee, Sanghun
An, Soomin
Choi, Woncheol
Eo, Wankyu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Adenocarcinoma of the ampulla of Vater (AAV) is a rare malignancy that has a better prognosis than other periampullary cancers.
However, the standard treatment for patients with relapsed or metastatic AAV has not been established.
We investigated the clinical feasibility of standardized allergen-removed Rhus verniciflua stokes (aRVS) extract for advanced or metastatic AAV.
Patients and Methods.
From July 2006 to April 2011, we retrospectively reviewed all patients with advanced AAV treated with aRVS extract alone.
After applying inclusion/exclusion criteria, 12 patients were eligible for the final analysis.
We assessed the progression-free survival (PFS) and overall survival (OS) of these patients during the follow-up period.
Results.
The median aRVS administration period was 147.0 days (range: 72–601 days).
The best tumor responses according to Response Evaluation Criteria in Solid Tumors were as follows: two with complete response, two with stable disease, and eight with progressive disease.
The median OS was 15.1 months (range: 4.9–25.1 months), and the median PFS was 3.0 months (range: 1.6–11.4 months).
Adverse reactions to the aRVS treatment were mostly mild and self-limiting.
Conclusions.
Prolonged survival was observed in patients with advanced AAV under the treatment of standardized aRVS extract without significant adverse effects.
American Psychological Association (APA)
Choi, Woncheol& An, Soomin& Kwon, Eunmi& Eo, Wankyu& Lee, Sanghun. 2013. Impact of Standardized Allergen-Removed Rhus verniciflua Stokes Extract on Advanced Adenocarcinoma of the Ampulla of Vater : A Case Series. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-454133
Modern Language Association (MLA)
Choi, Woncheol…[et al.]. Impact of Standardized Allergen-Removed Rhus verniciflua Stokes Extract on Advanced Adenocarcinoma of the Ampulla of Vater : A Case Series. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-454133
American Medical Association (AMA)
Choi, Woncheol& An, Soomin& Kwon, Eunmi& Eo, Wankyu& Lee, Sanghun. Impact of Standardized Allergen-Removed Rhus verniciflua Stokes Extract on Advanced Adenocarcinoma of the Ampulla of Vater : A Case Series. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-454133
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454133