Asystole after Orthotopic Lung Transplantation : Examining the Interaction of Cardiac Denervation and Dexmedetomidine
Joint Authors
Flynn, Brigid Colleen
Weyker, Paul David
Webb, Christopher Allen-John
Source
Case Reports in Anesthesiology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Dexmedetomidine is an α2-receptor agonist commonly used for sedation and analgesia in ICU patients.
Dexmedetomidine is known to provide sympatholysis and also to have direct atrioventricular and sinoatrial node inhibitory effects.
In rare instances, orthotopic lung transplantation has been associated with disruption of autonomic innervation of the heart.
The combination of this autonomic disruption and dexmedetomidine may be associated with severe bradycardia and/or asystole.
Since orthotopic lung transplant patients with parasympathetic denervation will not respond with increased heart rate to anticholinergic therapy, bradyarrhythmias must be recognized and promptly treated with direct acting beta agonists to avoid asystolic cardiac events.
American Psychological Association (APA)
Webb, Christopher Allen-John& Weyker, Paul David& Flynn, Brigid Colleen. 2012. Asystole after Orthotopic Lung Transplantation : Examining the Interaction of Cardiac Denervation and Dexmedetomidine. Case Reports in Anesthesiology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-454139
Modern Language Association (MLA)
Webb, Christopher Allen-John…[et al.]. Asystole after Orthotopic Lung Transplantation : Examining the Interaction of Cardiac Denervation and Dexmedetomidine. Case Reports in Anesthesiology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-454139
American Medical Association (AMA)
Webb, Christopher Allen-John& Weyker, Paul David& Flynn, Brigid Colleen. Asystole after Orthotopic Lung Transplantation : Examining the Interaction of Cardiac Denervation and Dexmedetomidine. Case Reports in Anesthesiology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-454139
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454139