Reactivation, Replay, and Preplay : How It Might All Fit Together
Joint Authors
Azizi, Amir H.
Cheng, Sen
Buhry, Laure
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-13
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Sequential activation of neurons that occurs during “offline” states, such as sleep or awake rest, is correlated with neural sequences recorded during preceding exploration phases.
This so-called reactivation, or replay, has been observed in a number of different brain regions such as the striatum, prefrontal cortex, primary visual cortex and, most prominently, the hippocampus.
Reactivation largely co-occurs together with hippocampal sharp-waves/ripples, brief high-frequency bursts in the local field potential.
Here, we first review the mounting evidence for the hypothesis that reactivation is the neural mechanism for memory consolidation during sleep.
We then discuss recent results that suggest that offline sequential activity in the waking state might not be simple repetitions of previously experienced sequences.
Some offline sequential activity occurs before animals are exposed to a novel environment for the first time, and some sequences activated offline correspond to trajectories never experienced by the animal.
We propose a conceptual framework for the dynamics of offline sequential activity that can parsimoniously describe a broad spectrum of experimental results.
These results point to a potentially broader role of offline sequential activity in cognitive functions such as maintenance of spatial representation, learning, or planning.
American Psychological Association (APA)
Buhry, Laure& Azizi, Amir H.& Cheng, Sen. 2011. Reactivation, Replay, and Preplay : How It Might All Fit Together. Neural Plasticity،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-454150
Modern Language Association (MLA)
Buhry, Laure…[et al.]. Reactivation, Replay, and Preplay : How It Might All Fit Together. Neural Plasticity No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-454150
American Medical Association (AMA)
Buhry, Laure& Azizi, Amir H.& Cheng, Sen. Reactivation, Replay, and Preplay : How It Might All Fit Together. Neural Plasticity. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-454150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454150