Sparse Regularization-Based Reconstruction for Bioluminescence Tomography Using a Multilevel Adaptive Finite Element Method
Joint Authors
Jiang, Yuchuan
Hou, Yanbin
Tian, Jie
Zhang, Qitan
Liu, Junting
Shen, Man
Chen, Duofang
He, Xiaowei
Source
International Journal of Biomedical Imaging
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Bioluminescence tomography (BLT) is a promising tool for studying physiological and pathological processes at cellular and molecular levels.
In most clinical or preclinical practices, fine discretization is needed for recovering sources with acceptable resolution when solving BLT with finite element method (FEM).
Nevertheless, uniformly fine meshes would cause large dataset and overfine meshes might aggravate the ill-posedness of BLT.
Additionally, accurately quantitative information of density and power has not been simultaneously obtained so far.
In this paper, we present a novel multilevel sparse reconstruction method based on adaptive FEM framework.
In this method, permissible source region gradually reduces with adaptive local mesh refinement.
By using sparse reconstruction with l1 regularization on multilevel adaptive meshes, simultaneous recovery of density and power as well as accurate source location can be achieved.
Experimental results for heterogeneous phantom and mouse atlas model demonstrate its effectiveness and potentiality in the application of quantitative BLT.
American Psychological Association (APA)
He, Xiaowei& Hou, Yanbin& Chen, Duofang& Jiang, Yuchuan& Shen, Man& Liu, Junting…[et al.]. 2010. Sparse Regularization-Based Reconstruction for Bioluminescence Tomography Using a Multilevel Adaptive Finite Element Method. International Journal of Biomedical Imaging،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-454156
Modern Language Association (MLA)
He, Xiaowei…[et al.]. Sparse Regularization-Based Reconstruction for Bioluminescence Tomography Using a Multilevel Adaptive Finite Element Method. International Journal of Biomedical Imaging No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-454156
American Medical Association (AMA)
He, Xiaowei& Hou, Yanbin& Chen, Duofang& Jiang, Yuchuan& Shen, Man& Liu, Junting…[et al.]. Sparse Regularization-Based Reconstruction for Bioluminescence Tomography Using a Multilevel Adaptive Finite Element Method. International Journal of Biomedical Imaging. 2010. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-454156
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454156