DV-Curve Representation of Protein Sequences and Its Application
Joint Authors
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Based on the detailed hydrophobic-hydrophilic(HP) model of amino acids, we propose dual-vector curve (DV-curve) representation of protein sequences, which uses two vectors to represent one alphabet of protein sequences.
This graphical representation not only avoids degeneracy, but also has good visualization no matter how long these sequences are, and can reflect the length of protein sequence.
Then we transform the 2D-graphical representation into a numerical characterization that can facilitate quantitative comparison of protein sequences.
The utility of this approach is illustrated by two examples: one is similarity/dissimilarity comparison among different ND6 protein sequences based on their DV-curve figures the other is the phylogenetic analysis among coronaviruses based on their spike proteins.
American Psychological Association (APA)
Deng, Wei& Luan, Yihui. 2014. DV-Curve Representation of Protein Sequences and Its Application. Computational and Mathematical Methods in Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-454204
Modern Language Association (MLA)
Deng, Wei& Luan, Yihui. DV-Curve Representation of Protein Sequences and Its Application. Computational and Mathematical Methods in Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-454204
American Medical Association (AMA)
Deng, Wei& Luan, Yihui. DV-Curve Representation of Protein Sequences and Its Application. Computational and Mathematical Methods in Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-454204
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454204