Adipokines and Osteoarthritis : Novel Molecules Involved in the Pathogenesis and Progression of Disease
Joint Authors
Gómez-Reino, Juan Jesus
Gómez, Rodolfo
Gualillo, Oreste
Conde, Javier
Scotece, Morena
Lopez, Veronica
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Obesity has been considered a risk factor for osteoarthritis and it is usually accepted that obesity contributes to the development and progression of osteoarthritis by increasing mechanical load of the joints.
Nevertheless, recent advances in the physiology of white adipose tissue evidenced that fat cells produce a plethora of factors, called adipokines, which have a critical role in the development of ostearthritis, besides to mechanical effects.
In this paper, we review the role of adipokines and highlight the cellular and molecular mechanisms at play in osteoarthritis elicited by adipokines.
We also emphasize how defining the role of adipokines has broadned our understanding of the diversity of factors involved in the genesis and progression of osteoarthritis in the hope of modifying it to prevent and treat diseases.
American Psychological Association (APA)
Conde, Javier& Scotece, Morena& Gómez, Rodolfo& Lopez, Veronica& Gómez-Reino, Juan Jesus& Gualillo, Oreste. 2011. Adipokines and Osteoarthritis : Novel Molecules Involved in the Pathogenesis and Progression of Disease. Arthritis،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-454207
Modern Language Association (MLA)
Conde, Javier…[et al.]. Adipokines and Osteoarthritis : Novel Molecules Involved in the Pathogenesis and Progression of Disease. Arthritis No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-454207
American Medical Association (AMA)
Conde, Javier& Scotece, Morena& Gómez, Rodolfo& Lopez, Veronica& Gómez-Reino, Juan Jesus& Gualillo, Oreste. Adipokines and Osteoarthritis : Novel Molecules Involved in the Pathogenesis and Progression of Disease. Arthritis. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-454207
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454207