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Modulation of Bacterial Multidrug Resistance Efflux Pumps of the Major Facilitator Superfamily
Joint Authors
Kumar, Sanath
Varela, Manuel F.
Mukherjee, Mun Mun
Source
International Journal of Bacteriology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-05
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Bacterial infections pose a serious public health concern, especially when an infectious disease has a multidrug resistant causative agent.
Such multidrug resistant bacteria can compromise the clinical utility of major chemotherapeutic antimicrobial agents.
Drug and multidrug resistant bacteria harbor several distinct molecular mechanisms for resistance.
Bacterial antimicrobial agent efflux pumps represent a major mechanism of clinical resistance.
The major facilitator superfamily (MFS) is one of the largest groups of solute transporters to date and includes a significant number of bacterial drug and multidrug efflux pumps.
We review recent work on the modulation of multidrug efflux pumps, paying special attention to those transporters belonging primarily to the MFS.
American Psychological Association (APA)
Kumar, Sanath& Mukherjee, Mun Mun& Varela, Manuel F.. 2013. Modulation of Bacterial Multidrug Resistance Efflux Pumps of the Major Facilitator Superfamily. International Journal of Bacteriology،Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-454226
Modern Language Association (MLA)
Kumar, Sanath…[et al.]. Modulation of Bacterial Multidrug Resistance Efflux Pumps of the Major Facilitator Superfamily. International Journal of Bacteriology No. 2013 (2013), pp.1-15.
https://search.emarefa.net/detail/BIM-454226
American Medical Association (AMA)
Kumar, Sanath& Mukherjee, Mun Mun& Varela, Manuel F.. Modulation of Bacterial Multidrug Resistance Efflux Pumps of the Major Facilitator Superfamily. International Journal of Bacteriology. 2013. Vol. 2013, no. 2013, pp.1-15.
https://search.emarefa.net/detail/BIM-454226
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454226