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Calculated Tumor Volume Is an Independent Predictor of Biochemical Recurrence in Patients Who Underwent Retropubic Radical Prostatectomy
Joint Authors
Chihara, Yoshitomo
Nakai, Yasushi
Hirayama, Akihide
Tanaka, Nobumichi
Tomioka, Atsushi
Anai, Satoshi
Konishi, Noboru
Hirao, Yoshihiko
Fujimoto, Kiyohide
Shimada, Keiji
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
The purpose of this study is to investigate whether the clinicopathological biopsy findings can predict the oncological outcome in patients who undergo radical prostatectomy.
Materials and Methods.
Between January 1997 and March 2006, 255 patients with clinically localized adenocarcinoma of the prostate (clinical T1-3N0M0) who had undergone retropubic radical prostatectomy were enrolled in this study.
None of the patients received neoadjuvant or adjuvant therapy.
Clinicopathological parameters were assessed to determine a predictive parameter of biochemical recurrence.
Results.
Of the total 255 patients, 77 showed biochemical recurrence during the follow-up period.
The estimated 5-year overall survival, 5-year cause-specific survival, and 5-year biochemical recurrence-free survival rates were 97.7%, 99.5%, and 67.3%, respectively.
Multivariate analysis using the Cox proportional hazards model showed that calculated cancer volume was an independent predictor among the preoperative clinicopathological parameters (P<0.05).
SVI and PSM were independent predictors among the postoperative parameters (SVI; P<0.001, PSM; P=0.049).
Among the significant preoperative and postoperative parameters, calculated cancer volume remained an independent predictive parameter in multivariate analysis (P<0.01).
Conclusions.
Tumor volume, as calculated by preoperative parameters, is an independent predictor of biochemical recurrence in patients who had undergone radical prostatectomy.
American Psychological Association (APA)
Tanaka, Nobumichi& Fujimoto, Kiyohide& Hirayama, Akihide& Nakai, Yasushi& Chihara, Yoshitomo& Anai, Satoshi…[et al.]. 2012. Calculated Tumor Volume Is an Independent Predictor of Biochemical Recurrence in Patients Who Underwent Retropubic Radical Prostatectomy. Advances in Urology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-454231
Modern Language Association (MLA)
Tanaka, Nobumichi…[et al.]. Calculated Tumor Volume Is an Independent Predictor of Biochemical Recurrence in Patients Who Underwent Retropubic Radical Prostatectomy. Advances in Urology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-454231
American Medical Association (AMA)
Tanaka, Nobumichi& Fujimoto, Kiyohide& Hirayama, Akihide& Nakai, Yasushi& Chihara, Yoshitomo& Anai, Satoshi…[et al.]. Calculated Tumor Volume Is an Independent Predictor of Biochemical Recurrence in Patients Who Underwent Retropubic Radical Prostatectomy. Advances in Urology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-454231
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454231