Differences in Metabolites of Different Tongue Coatings in Patients with Chronic Hepatitis B
Joint Authors
Sun, Shu-jun
Hu, Yi-Yang
Zheng, Ning-ning
Jiang, Jian
Feng, Qin
Zhang, Yong-Yu
Fang, Jun-wei
Zhao, Yu
Peng, Jing-hua
Su, Shi-Bing
Cao, Hui-juan
Liu, Ping
Gou, Xiao-jun
Dai, Jian-ye
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-04-17
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Tongue coating is one of the important foundations of tongue diagnosis in traditional Chinese medicine (TCM) and plays an important role in reflecting the occurrence, development, and prognosis of the disease.
However, its material basis is still poorly understood.
In this study, a urinary metabonomic method based on gas chromatography coupled to mass spectrometry (GC/MS) was developed.
The distinct clustering in metabolic profile was observed from Group A (thick yellow coating in patients with chronic hepatitis B), Group B (thick white coating in patients with chronic hepatitis B), and Group C (thin white coating with healthy humans) using orthogonal projections to latent structures (OPLS).
Based on the variable of importance in the project (VIP) values, some significantly changed metabolites have been identified.
These changes were related to the disturbance in energy metabolism, amino acid metabolism, nucleotide metabolism, and gut microflora, which were helpful to understand the material basis leading to the formation of tongue coating.
This study demonstrated that tongue coating may have an objective material basis.
American Psychological Association (APA)
Zhao, Yu& Gou, Xiao-jun& Dai, Jian-ye& Peng, Jing-hua& Feng, Qin& Sun, Shu-jun…[et al.]. 2013. Differences in Metabolites of Different Tongue Coatings in Patients with Chronic Hepatitis B. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-454290
Modern Language Association (MLA)
Zhao, Yu…[et al.]. Differences in Metabolites of Different Tongue Coatings in Patients with Chronic Hepatitis B. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-12.
https://search.emarefa.net/detail/BIM-454290
American Medical Association (AMA)
Zhao, Yu& Gou, Xiao-jun& Dai, Jian-ye& Peng, Jing-hua& Feng, Qin& Sun, Shu-jun…[et al.]. Differences in Metabolites of Different Tongue Coatings in Patients with Chronic Hepatitis B. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-12.
https://search.emarefa.net/detail/BIM-454290
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454290