Brief Review of the Role of Glycogen Synthase Kinase-3β in Amyotrophic Lateral Sclerosis
Joint Authors
Koh, Seong-Ho
Baek, Wonki
Kim, Seung H.
Source
Neurology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Glycogen synthase kinase-3β (GSK-3β) is known to affect a diverse range of biological functions controlling gene expression, cellular architecture, and apoptosis.
GSK-3β has recently been identified as one of the important pathogenic mechanisms in motor neuronal death related to amyotrophic lateral sclerosis (ALS).
Therefore, the development of methods to control GSK-3β could be helpful in postponing the symptom progression of ALS.
Here we discuss the known roles of GSK-3β in motor neuronal cell death in ALS and the possibility of employing GSK-3β modulators as a new therapeutic strategy.
American Psychological Association (APA)
Koh, Seong-Ho& Baek, Wonki& Kim, Seung H.. 2011. Brief Review of the Role of Glycogen Synthase Kinase-3β in Amyotrophic Lateral Sclerosis. Neurology Research International،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-454374
Modern Language Association (MLA)
Koh, Seong-Ho…[et al.]. Brief Review of the Role of Glycogen Synthase Kinase-3β in Amyotrophic Lateral Sclerosis. Neurology Research International No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-454374
American Medical Association (AMA)
Koh, Seong-Ho& Baek, Wonki& Kim, Seung H.. Brief Review of the Role of Glycogen Synthase Kinase-3β in Amyotrophic Lateral Sclerosis. Neurology Research International. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-454374
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454374