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Myelodysplastic Syndrome with Myelofibrosis Transformed to a Precursor B-Cell Acute Lymphoblastic Leukemia : A Case Report with Review of the Literature
Joint Authors
Fu, Kai
Algarni, Ayed A.
Akhtari, Mojtaba
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Myelodysplastic syndromes (MDS) comprise a group of heterogeneous clonal hematopoietic cell disorders characterized by cytopenias, bone marrow hypercellularity, and increased risk of transformation to acute leukemias.
MDS usually transformed to acute myeloid leukemia, and transformation to acute lymphoblastic leukemia (ALL) is rare.
Herein, we report a unique patient who presented with MDS with myelofibrosis.
Two months after the initial diagnosis, she progressed to a precursor B-cell acute lymphoblastic leukemia.
She was treated with induction therapy followed by allogenic stem cell transplantation.
She was alive and doing well upon last followup.
We have also reviewed the literature and discussed the clinicopathologic features of 36 MDS patients who progressed to ALL reported in the literature.
American Psychological Association (APA)
Algarni, Ayed A.& Akhtari, Mojtaba& Fu, Kai. 2012. Myelodysplastic Syndrome with Myelofibrosis Transformed to a Precursor B-Cell Acute Lymphoblastic Leukemia : A Case Report with Review of the Literature. Case Reports in Hematology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-454566
Modern Language Association (MLA)
Algarni, Ayed A.…[et al.]. Myelodysplastic Syndrome with Myelofibrosis Transformed to a Precursor B-Cell Acute Lymphoblastic Leukemia : A Case Report with Review of the Literature. Case Reports in Hematology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-454566
American Medical Association (AMA)
Algarni, Ayed A.& Akhtari, Mojtaba& Fu, Kai. Myelodysplastic Syndrome with Myelofibrosis Transformed to a Precursor B-Cell Acute Lymphoblastic Leukemia : A Case Report with Review of the Literature. Case Reports in Hematology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-454566
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454566