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Fluorescence-Guided Surgery and Biopsy in Gliomas with an Exoscope System
Joint Authors
Piquer, José
Rodriguez, Ruben
Rovira, Vicente
Riesgo, Pedro
Cremades, Antonio
Llácer, Jose L.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-21
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
The introduction of fluorescence-guided resection allows a better identification of tumor tissue and its more radical resection.
We describe our experience with a modified exoscope to detect 5 ALA-induced fluorescence in neuronavigation-guided brain surgery or biopsy of malignant brain tumors.
Methods.
Thirty-eight patients with a suspected preoperative diagnosis of high-grade astrocytoma were included.
We used a neuronavigation device and a high-definition exoscope system with a built-in filter to detect 5-ALA fluorescence in all cases.
Thirty patients underwent craniotomy with tumor resection and 8 underwent frameless stereotactic brain biopsy.
Results.
Histopathological diagnosis confirmed the presence of high-grade gliomas in 34 patients.
Total resection was achieved in 23 cases and subtotal in 7.
No relevant complications related to the administration of 5-ALA were detected.
Conclusions.
The use of the exoscope in 5-ALA fluorescence-guided tumor surgery has twofold implications: during brain tumor surgery it can be considered a valuable tool to achieve a more radical resection of the lesion, and when applied to a biopsy of a suspected brain high-grade glioma, it decreases the possibility of a negative biopsy.
American Psychological Association (APA)
Piquer, José& Llácer, Jose L.& Rovira, Vicente& Riesgo, Pedro& Rodriguez, Ruben& Cremades, Antonio. 2014. Fluorescence-Guided Surgery and Biopsy in Gliomas with an Exoscope System. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-454601
Modern Language Association (MLA)
Piquer, José…[et al.]. Fluorescence-Guided Surgery and Biopsy in Gliomas with an Exoscope System. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-454601
American Medical Association (AMA)
Piquer, José& Llácer, Jose L.& Rovira, Vicente& Riesgo, Pedro& Rodriguez, Ruben& Cremades, Antonio. Fluorescence-Guided Surgery and Biopsy in Gliomas with an Exoscope System. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-454601
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454601