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Safety Characterization and Antimicrobial Properties of Kefir-Isolated Lactobacillus kefiri
Joint Authors
De Antoni, Graciela
Díaz, Mariángeles
Urdaci, María C.
Racedo, Silvia M.
Serradell, María de los Angeles
Carasi, Paula
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Lactobacilli are generally regarded as safe; however, certain strains have been associated with cases of infection.
Our workgroup has already assessed many functional properties of Lactobacillus kefiri, but parameters regarding safety must be studied before calling them probiotics.
In this work, safety aspects and antimicrobial activity of L.
kefiri strains were studied.
None of the L.
kefiri strains tested caused α- or β-hemolysis.
All the strains were susceptible to tetracycline, clindamycin, streptomycin, ampicillin, erythromycin, kanamycin, and gentamicin; meanwhile, two strains were resistant to chloramphenicol.
On the other hand, all L.
kefiri strains were able to inhibit both Gram(+) and Gram(−) pathogens.
Regarding the in vitro results, L.
kefiri CIDCA 8348 was selected to perform in vivo studies.
Mice treated daily with an oral dose of 108 CFU during 21 days showed no signs of pain, lethargy, dehydration, or diarrhea, and the histological studies were consistent with those findings.
Moreover, no differences in proinflammatory cytokines secretion were observed between treated and control mice.
No translocation of microorganisms to blood, spleen, or liver was observed.
Regarding these findings, L.
kefiri CIDCA 8348 is a microorganism isolated from a dairy product with a great potential as probiotic for human or animal use.
American Psychological Association (APA)
Carasi, Paula& Díaz, Mariángeles& Racedo, Silvia M.& De Antoni, Graciela& Urdaci, María C.& Serradell, María de los Angeles. 2014. Safety Characterization and Antimicrobial Properties of Kefir-Isolated Lactobacillus kefiri. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-454699
Modern Language Association (MLA)
Carasi, Paula…[et al.]. Safety Characterization and Antimicrobial Properties of Kefir-Isolated Lactobacillus kefiri. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-454699
American Medical Association (AMA)
Carasi, Paula& Díaz, Mariángeles& Racedo, Silvia M.& De Antoni, Graciela& Urdaci, María C.& Serradell, María de los Angeles. Safety Characterization and Antimicrobial Properties of Kefir-Isolated Lactobacillus kefiri. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-454699
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454699