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High-Risk Sexual Behavior Is Associated with Postexposure Prophylaxis Nonadherence among Men Who Have Sex with Men Enrolled in a Combination Prevention Intervention
Joint Authors
Reback, Cathy J.
Fletcher, Jesse B.
Le, Hung
Landovitz, Raphael J.
Rusow, Joshua A.
Source
Journal of Sexually Transmitted Diseases
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Methamphetamine use among men who have sex with men (MSM) is associated with increased HIV prevalence, due to increased engagement in high-risk sexual behavior.
Fifty-three HIV-negative, methamphetamine-using MSM were enrolled in a biobehavioral combination prevention intervention in Los Angeles, CA, to assess the feasibility of administering postexposure prophylaxis (PEP) in combination with contingency management (CM) to prevent HIV seroconversion.
The study combined a CM behavioral intervention targeting reductions in methamphetamine use with a PEP biomedical intervention for HIV prevention.
Those who reported recent exposure to HIV were initiated on tenofovir/emtricitabine- (Truvada-) based PEP (n=35).
This secondary analysis sought to determine whether sexual risk taking was associated with PEP adherence.
Regression analyses controlling for participant sociodemographics demonstrated that, at baseline, increased number of lifetime sexually transmitted diseases (STDs; Coef.
= −0.07; 95% CI= (−0.12) – (−0.01)) and recent episodes of unprotected anal intercourse (UAI; Coef.
= −0.01; 95% CI= (−.01) – (−0.002)) were associated with reductions in medication adherence.
Given these associations between baseline sexual risk and PEP adherence, providers working with high-risk MSM may look to target reductions in sexual risk taking; this will reduce direct risk of HIV infection and may work to optimize medication adherence in the case of PEP initiation.
American Psychological Association (APA)
Fletcher, Jesse B.& Rusow, Joshua A.& Le, Hung& Landovitz, Raphael J.& Reback, Cathy J.. 2013. High-Risk Sexual Behavior Is Associated with Postexposure Prophylaxis Nonadherence among Men Who Have Sex with Men Enrolled in a Combination Prevention Intervention. Journal of Sexually Transmitted Diseases،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-454835
Modern Language Association (MLA)
Fletcher, Jesse B.…[et al.]. High-Risk Sexual Behavior Is Associated with Postexposure Prophylaxis Nonadherence among Men Who Have Sex with Men Enrolled in a Combination Prevention Intervention. Journal of Sexually Transmitted Diseases No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-454835
American Medical Association (AMA)
Fletcher, Jesse B.& Rusow, Joshua A.& Le, Hung& Landovitz, Raphael J.& Reback, Cathy J.. High-Risk Sexual Behavior Is Associated with Postexposure Prophylaxis Nonadherence among Men Who Have Sex with Men Enrolled in a Combination Prevention Intervention. Journal of Sexually Transmitted Diseases. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-454835
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454835