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Diagnostic Usefulness of Real-Time Elastography for Liver Fibrosis in Chronic Viral Hepatitis B and C
Joint Authors
Kim, Min Ju
Kim, Young Woon
Nam, Soon Woo
Chung, Kyu Won
Park, Eun Su
Kwon, Jung Hyun
Jang, Jeong Won
Oh, Byong Sun
Source
Gastroenterology Research and Practice
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The aim of this study was to investigate the diagnostic usefulness of real-time elastography (RTE) for liver fibrosis in chronic viral hepatitis B (CHB) and C (CHC).
Fifty-one and thirty-two of the patients were diagnosed with CHB and CHC, respectively.
Enrolled patients underwent liver biopsy and RTE.
The FIB-4 index and aspartate transaminase-to-platelet ratio index (APRI) were also measured.
The liver fibrosis index (LFI) by RTE increased significantly with the Knodell fibrosis stage: 3.14±0.62 for F0, 3.28 ± 0.42 for F1, 3.43 ± 0.53 for F3, and 4.09 ± 1.03 for F4 (P=0.000).
LFI as well as APRI, FIB-4, platelet, albumin, and prothrombin time showed the difference in patients with advanced fibrosis (≥F3) and those with mild fibrosis (≤F1).
In addition, RTE had better discrimination power between ≥F3 and F4 than between FIB-4 and APRI.
In CHC patients, the area under receiver operating characteristic curves of RTE for advanced fibrosis was higher than that in CHB patients (0.795 versus 0.641).
RTE is useful for the assessment of advanced fibrosis in patients with CHB and CHC and has better discrimination power than other serologic markers.
American Psychological Association (APA)
Kim, Young Woon& Kwon, Jung Hyun& Jang, Jeong Won& Kim, Min Ju& Oh, Byong Sun& Chung, Kyu Won…[et al.]. 2014. Diagnostic Usefulness of Real-Time Elastography for Liver Fibrosis in Chronic Viral Hepatitis B and C. Gastroenterology Research and Practice،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-454836
Modern Language Association (MLA)
Kim, Young Woon…[et al.]. Diagnostic Usefulness of Real-Time Elastography for Liver Fibrosis in Chronic Viral Hepatitis B and C. Gastroenterology Research and Practice No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-454836
American Medical Association (AMA)
Kim, Young Woon& Kwon, Jung Hyun& Jang, Jeong Won& Kim, Min Ju& Oh, Byong Sun& Chung, Kyu Won…[et al.]. Diagnostic Usefulness of Real-Time Elastography for Liver Fibrosis in Chronic Viral Hepatitis B and C. Gastroenterology Research and Practice. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-454836
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454836