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Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome : A Comprehensive Review
Joint Authors
Kallergis, Eleftherios M.
Simantirakis, Emmanuel N.
Vardas, Panos E.
Kochiadakis, George E.
Goudis, Christos A.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Long QT syndrome is characterized by prolongation of the corrected QT (QTc) interval on the surface electrocardiogram and is associated with precipitation of torsade de pointes (TdP), a polymorphic ventricular tachycardia that may cause sudden death.
Acquired long QT syndrome describes pathologic excessive prolongation of the QT interval, upon exposure to an environmental stressor, with reversion back to normal following removal of the stressor.
The most common environmental stressor in acquired long QT syndrome is drug therapy.
Acquired long QT syndrome is an important issue for clinicians and a significant public health problem concerning the large number of drugs with this adverse effect with a potentially fatal outcome, the large number of patients exposed to these drugs, and our inability to predict the risk for a given individual.
In this paper, we focus on mechanisms underlying QT prolongation, risk factors for torsades de pointes and describe the short- and long-term treatment of acquired long QT syndrome.
American Psychological Association (APA)
Kallergis, Eleftherios M.& Goudis, Christos A.& Simantirakis, Emmanuel N.& Kochiadakis, George E.& Vardas, Panos E.. 2012. Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome : A Comprehensive Review. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-454908
Modern Language Association (MLA)
Kallergis, Eleftherios M.…[et al.]. Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome : A Comprehensive Review. The Scientific World Journal No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-454908
American Medical Association (AMA)
Kallergis, Eleftherios M.& Goudis, Christos A.& Simantirakis, Emmanuel N.& Kochiadakis, George E.& Vardas, Panos E.. Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome : A Comprehensive Review. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-454908
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454908