Case Report : Safety and Efficacy of Tocilizumab in a Patient with Rheumatoid Arthritis and Chronic Hepatitis C
Joint Authors
Iebba, Filippo
Montella, Francesco
Tarasi, Agapito
Montella, Tatiana
Leti, Wilma
Di Sora, Fiorella
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Tocilizumab is a monoclonal humanized anti-IL-6-receptor antibody used for the treatment of rheumatoid arthritis.
The safety of tocilizumab in HCV patients is an open question.
We report on safety and efficacy of tocilizumab in a 71-year-old female with rheumatoid arthritis and chronic hepatitis C.
Monotherapy with tocilizumab (8 mg/kg every 4 weeks, i.v.) was prescribed after the discontinuation, determined by clinical inefficacy, of anti-TNF-alfa agents (adalimumab and, subsequently, etanercept).
We have registered an optimal and rapid clinical response to tocilizumab with early remission (SDAI <3.3 since 4 weeks).
The safety was good with no adverse events and maintenance, during a six-month followup, of normal liver enzymes.
These data suggest a good safety profile of tocilizumab in patients with rheumatoid arthritis and chronic hepatitis C virus pathology.
American Psychological Association (APA)
Iebba, Filippo& Di Sora, Fiorella& Tarasi, Agapito& Leti, Wilma& Montella, Tatiana& Montella, Francesco. 2012. Case Report : Safety and Efficacy of Tocilizumab in a Patient with Rheumatoid Arthritis and Chronic Hepatitis C. Case Reports in Medicine،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-454918
Modern Language Association (MLA)
Iebba, Filippo…[et al.]. Case Report : Safety and Efficacy of Tocilizumab in a Patient with Rheumatoid Arthritis and Chronic Hepatitis C. Case Reports in Medicine No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-454918
American Medical Association (AMA)
Iebba, Filippo& Di Sora, Fiorella& Tarasi, Agapito& Leti, Wilma& Montella, Tatiana& Montella, Francesco. Case Report : Safety and Efficacy of Tocilizumab in a Patient with Rheumatoid Arthritis and Chronic Hepatitis C. Case Reports in Medicine. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-454918
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454918
