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Inflammation and Pharmacological Treatment in Diabetic Retinopathy
Joint Authors
Ljubić, Spomenka
Gverović Antunica, Antonela
Salopek Rabatić, Jasminka
Tomić, Martina
Kaštelan, Snježana
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-10-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Diabetic retinopathy (DR), the most common microvascular complication of diabetes mellitus, is estimated to be the leading cause of new blindness in the working population of developed countries.
Primary interventions such as intensive glycemic control, strict blood pressure regulation, and lipid-modifying therapy as well as local ocular treatment (laser photocoagulation and pars plana vitrectomy) can significantly reduce the risk of retinopathy occurrence and progression.
Considering the limitations of current DR treatments development of new therapeutic strategies, it becomes necessary to focus on pharmacological treatment.
Currently, there is increasing evidence that inflammatory processes have a considerable role in the pathogenesis of DR with multiple studies showing an association of various systemic as well as local (vitreous and aqueous fluid) inflammatory factors and the progression of DR.
Since inflammation is identified as a relevant mechanism, significant effort has been directed to the development of new concepts for the prevention and treatment of DR acting on the inflammatory processes and the use of pharmacological agents with anti-inflammatory effect.
Inhibiting the inflammatory pathway could be an appealing treatment option for DR in future practices, and as further prospective randomized clinical trials accumulate data, the role and guidelines of anti-inflammatory pharmacologic treatments will become clearer.
American Psychological Association (APA)
Kaštelan, Snježana& Tomić, Martina& Gverović Antunica, Antonela& Salopek Rabatić, Jasminka& Ljubić, Spomenka. 2013. Inflammation and Pharmacological Treatment in Diabetic Retinopathy. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-454987
Modern Language Association (MLA)
Kaštelan, Snježana…[et al.]. Inflammation and Pharmacological Treatment in Diabetic Retinopathy. Mediators of Inflammation No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-454987
American Medical Association (AMA)
Kaštelan, Snježana& Tomić, Martina& Gverović Antunica, Antonela& Salopek Rabatić, Jasminka& Ljubić, Spomenka. Inflammation and Pharmacological Treatment in Diabetic Retinopathy. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-454987
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454987