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Age-Related Changes in Trabecular and Cortical Bone Microstructure
Joint Authors
Kubo, Kin-Ya
Zhou, Xiangrong
Chen, Huayue
Fujita, Hiroshi
Onozuka, Minoru
Source
International Journal of Endocrinology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The elderly population has substantially increased worldwide.
Aging is a complex process, and the effects of aging are myriad and insidious, leading to progressive deterioration of various organs, including the skeleton.
Age-related bone loss and resultant osteoporosis in the elderly population increase the risk for fractures and morbidity.
Osteoporosis is one of the most common conditions associated with aging, and age is an independent risk factor for osteoporotic fractures.
With the development of noninvasive imaging techniques such as computed tomography (CT), micro-CT, and high resolution peripheral quantitative CT (HR-pQCT), imaging of the bone architecture provides important information about age-related changes in bone microstructure and estimates of bone strength.
In the past two decades, studies of human specimens using imaging techniques have revealed decreased bone strength in older adults compared with younger adults.
The present paper addresses recently studied age-related changes in trabecular and cortical bone microstructure based primarily on HR-pQCT and micro-CT.
We specifically focus on the three-dimensional microstructure of the vertebrae, femoral neck, and distal radius, which are common osteoporotic fracture sites.
American Psychological Association (APA)
Chen, Huayue& Zhou, Xiangrong& Fujita, Hiroshi& Onozuka, Minoru& Kubo, Kin-Ya. 2013. Age-Related Changes in Trabecular and Cortical Bone Microstructure. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-454996
Modern Language Association (MLA)
Chen, Huayue…[et al.]. Age-Related Changes in Trabecular and Cortical Bone Microstructure. International Journal of Endocrinology No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-454996
American Medical Association (AMA)
Chen, Huayue& Zhou, Xiangrong& Fujita, Hiroshi& Onozuka, Minoru& Kubo, Kin-Ya. Age-Related Changes in Trabecular and Cortical Bone Microstructure. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-454996
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-454996