Comparative Gamma Delta T Cell Immunology : A Focus on Mycobacterial Disease in Cattle
Joint Authors
Plattner, Brandon L.
Hostetter, Jesse M.
Source
Veterinary Medicine International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A theme among many pathogenic mycobacterial species affecting both humans and animals is a prolonged asymptomatic or latent period that can last years to decades.
The mechanisms that favor progression to active disease are not well understood.
Pathogen containment is often associated with an effective cell-mediated or T-helper 1 immune profile.
With certain pathogenic mycobacteria, such as Mycobacterium avium subspecies paratuberculosis, a shift to active clinical disease is associated with loss of T-helper 1 immunity and development of an ineffective humoral or T-helper 2 immune response.
Recently γδ T cells have been shown to play a role early in mycobacterial infections and have been hypothesized to influence disease outcome.
The purpose of this paper is to compare recent advancements in our understanding of γδ T cells in humans, cattle, and mice and to discuss roles of γδ T cells in host response to mycobacterial infection.
American Psychological Association (APA)
Plattner, Brandon L.& Hostetter, Jesse M.. 2011. Comparative Gamma Delta T Cell Immunology : A Focus on Mycobacterial Disease in Cattle. Veterinary Medicine International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-455119
Modern Language Association (MLA)
Plattner, Brandon L.& Hostetter, Jesse M.. Comparative Gamma Delta T Cell Immunology : A Focus on Mycobacterial Disease in Cattle. Veterinary Medicine International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-455119
American Medical Association (AMA)
Plattner, Brandon L.& Hostetter, Jesse M.. Comparative Gamma Delta T Cell Immunology : A Focus on Mycobacterial Disease in Cattle. Veterinary Medicine International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-455119
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455119