Phytochemical Compositions and Antioxidant and Anti-Inflammatory Activities of Crude Extracts from Ficus pandurata H. (Moraceae)
Joint Authors
Hu, Changfeng
Zhang, Xiaoping
Lv, Huiqing
Jiang, Kezhi
Xie, Zhijun
Wen, Chengping
Chen, XueZhi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Ficus pandurata H.
(Moraceae) is widely used in traditional Chinese medicine as a healthy food condiment or a medicine for treatment of various diseases including inflammation.
Objective.
The purpose of the present study is to investigate the phytochemical compositions and antioxidant and anti-inflammatory activities of crude water (FPW) and ethanolic extracts (FPE) from Ficus pandurata H.
Methods.
Phytochemical compositions were identified by a high-performance liquid chromatography-electrospray ionization-mass spectrometry method (HPLC-ESI-MS).
The antioxidant activities were evaluated by diphenylpicrylhydrazyl (DPPH) and hydroxyl radical assays, and the anti-inflammatory activities were evaluated by paw edema and levels of inflammatory mediator TNF-α and PGE2 in monosodium urate (MSU) crystal-induced rats.
Results.
Six compounds were identified by HPLC-MS method, and abundance of phenolics was found in FPE.
The FPE showed concentration-dependent-significant scavenging of DPPH and hydroxyl radicals with IC50 values 118.4 and 192.9 μg/mL, respectively.
The FPE treatment significantly inhibited the paw edema and the production of TNF-α and PGE2 in MSU crystal-induced rats.
Conclusion.
The FPE exerted stronger antioxidant and anti-inflammatory activities which may be attributed to its high phenolic content.
American Psychological Association (APA)
Lv, Huiqing& Zhang, Xiaoping& Chen, XueZhi& Xie, Zhijun& Hu, Changfeng& Wen, Chengping…[et al.]. 2013. Phytochemical Compositions and Antioxidant and Anti-Inflammatory Activities of Crude Extracts from Ficus pandurata H. (Moraceae). Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-455175
Modern Language Association (MLA)
Lv, Huiqing…[et al.]. Phytochemical Compositions and Antioxidant and Anti-Inflammatory Activities of Crude Extracts from Ficus pandurata H. (Moraceae). Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-455175
American Medical Association (AMA)
Lv, Huiqing& Zhang, Xiaoping& Chen, XueZhi& Xie, Zhijun& Hu, Changfeng& Wen, Chengping…[et al.]. Phytochemical Compositions and Antioxidant and Anti-Inflammatory Activities of Crude Extracts from Ficus pandurata H. (Moraceae). Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-455175
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455175