Usefulness of Noninvasive Predictors of Oesophageal Varices in Black African Cirrhotic Patients in Côte d'Ivoire (West Africa)
Joint Authors
Bathaix, Fulgence Yao
Bangoura, Aboubacar Demba
Kissi, Henriette Ya
Attia, Alain Koffi
Camara, Mathieu Benoit
Mahassadi, Alassan Kouamé
Allah-Kouadio, Emile
Doffou, Stanislas
Touré, Abdoulaye
Assi, Constant
Konaté, Issa
Ndri-Yoman, Thérèse Aya
Source
Gastroenterology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Aims.
To determine the usefulness of platelet count (PC), spleen diameter (SD) and platelet count/spleen diameter ratio (PC/SD ratio) for the prediction of oesophageal varices (OV) and large OV in black African patients with cirrhosis in Côte d’Ivoire.
Materials and Methods.
Study was conducted in a training sample (111 patients) and in a validation sample (91 patients).
Results.
Factors predicting OV were sex: (OR=0.08, P=0.0003), PC (OR = 12.4, P=0.0003), SD (OR = 1.04, P=0.002) in the training sample.
The AUROCs (±SE) of the model (cutoff ≥ 0.6), PC (cutoff < 110500), SD (cutoff > 140) and PC/SD ratio (cutoff ≤ 868) were, respectively; 0.879 ± 0.04, 0.768 ± 0.06, 0.679 ± 0.06, 0.793 ± 0.06.
For the prediction of large OV, the model’s AUROC (0.850 ± 0.05) was superior to that of PC (0.688 ± 0.06), SD (0.732 ± 0.05) and PC/SD ratio (0.752 ± 0.06).
In the validation sample, with PC, PC/SD ratio and the model, upper digestive endoscopy could be obviated respectively in 45.1, 45.1, and 44% of cirrhotic patients.
Prophylactic treatment with beta blockers could be started undoubtedly respectively in 36.3, 41.8 and 28.6% of them as having large OV.
Conclusion.
Non-invasive means could be used to monitor cirrhotic patients and consider treatment in African regions lacking endoscopic facilities.
American Psychological Association (APA)
Mahassadi, Alassan Kouamé& Bathaix, Fulgence Yao& Assi, Constant& Bangoura, Aboubacar Demba& Allah-Kouadio, Emile& Kissi, Henriette Ya…[et al.]. 2012. Usefulness of Noninvasive Predictors of Oesophageal Varices in Black African Cirrhotic Patients in Côte d'Ivoire (West Africa). Gastroenterology Research and Practice،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-455304
Modern Language Association (MLA)
Mahassadi, Alassan Kouamé…[et al.]. Usefulness of Noninvasive Predictors of Oesophageal Varices in Black African Cirrhotic Patients in Côte d'Ivoire (West Africa). Gastroenterology Research and Practice No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-455304
American Medical Association (AMA)
Mahassadi, Alassan Kouamé& Bathaix, Fulgence Yao& Assi, Constant& Bangoura, Aboubacar Demba& Allah-Kouadio, Emile& Kissi, Henriette Ya…[et al.]. Usefulness of Noninvasive Predictors of Oesophageal Varices in Black African Cirrhotic Patients in Côte d'Ivoire (West Africa). Gastroenterology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-455304
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455304