Infliximab-Induced Hypothyroidism : A Novel Case and Postulations concerning the Mechanism
Joint Authors
Cerniglia, Brett
Judson, Marc A.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-2, 2 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-19
Country of Publication
Egypt
No. of Pages
2
Main Subjects
Abstract EN
We report a patient with cutaneous sarcoidosis who developed hypothyroidism following 17 months of infliximab therapy.
To our knowledge, this is the first reported case of hypothyroidism following infliximab administration.
While it is possible that the patient’s hypothyroidism was unrelated to the use of infliximab, the time course and lack of alternative explanations make such an association plausible.
We postulate that hypothyroidism in this patient may have been related to the development of autoantibodies to infliximab that triggered the development of an autoimmune thyroiditis.
Regardless of the mechanism, we would encourage clinicians to keep the potential mechanisms of TNF-α in mind when treating patients with TNF-α antagonist medications.
American Psychological Association (APA)
Cerniglia, Brett& Judson, Marc A.. 2013. Infliximab-Induced Hypothyroidism : A Novel Case and Postulations concerning the Mechanism. Case Reports in Medicine،Vol. 2013, no. 2013, pp.1-2.
https://search.emarefa.net/detail/BIM-455351
Modern Language Association (MLA)
Cerniglia, Brett& Judson, Marc A.. Infliximab-Induced Hypothyroidism : A Novel Case and Postulations concerning the Mechanism. Case Reports in Medicine No. 2013 (2013), pp.1-2.
https://search.emarefa.net/detail/BIM-455351
American Medical Association (AMA)
Cerniglia, Brett& Judson, Marc A.. Infliximab-Induced Hypothyroidism : A Novel Case and Postulations concerning the Mechanism. Case Reports in Medicine. 2013. Vol. 2013, no. 2013, pp.1-2.
https://search.emarefa.net/detail/BIM-455351
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455351