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Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy
Joint Authors
Ellis, Matthew J.
Ma, Cynthia X.
Peddi, Parvin F.
Source
International Journal of Breast Cancer
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Triple negative breast cancer is an aggressive form of breast cancer with limited treatment options and is without proven targeted therapy.
Understanding the molecular basis of triple negative breast cancer is crucial for effective new drug development.
Recent genomewide gene expression and DNA sequencing studies indicate that this cancer type is composed of a molecularly heterogeneous group of diseases that carry multiple somatic mutations and genomic structural changes.
These findings have implications for therapeutic target identification and the design of future clinical trials for this aggressive group of breast cancer.
American Psychological Association (APA)
Peddi, Parvin F.& Ellis, Matthew J.& Ma, Cynthia X.. 2011. Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy. International Journal of Breast Cancer،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-455371
Modern Language Association (MLA)
Peddi, Parvin F.…[et al.]. Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy. International Journal of Breast Cancer No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-455371
American Medical Association (AMA)
Peddi, Parvin F.& Ellis, Matthew J.& Ma, Cynthia X.. Molecular Basis of Triple Negative Breast Cancer and Implications for Therapy. International Journal of Breast Cancer. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-455371
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455371