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Exhaled Breath Condensate : A Promising Source for Biomarkers of Lung Disease
Joint Authors
Yeligar, Samantha M.
Brown, Lou Ann S.
Liang, Yan
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Exhaled breath condensate (EBC) has been increasingly studied as a noninvasive research method for sampling the alveolar and airway space and is recognized as a promising source of biomarkers of lung diseases.
Substances measured in EBC include oxidative stress and inflammatory mediators, such as arachidonic acid derivatives, reactive oxygen/nitrogen species, reduced and oxidized glutathione, and inflammatory cytokines.
Although EBC has great potential as a source of biomarkers in many lung diseases, the low concentrations of compounds within the EBC present challenges in sample collection and analysis.
Although EBC is viewed as a noninvasive method for sampling airway lining fluid (ALF), validation is necessary to confirm that EBC truly represents the ALF.
Likewise, a dilution factor for the EBC is needed in order to compare across subjects and determine changes in the ALF.
The aims of this paper are to address the characteristics of EBC; strategies to standardize EBC sample collection and review available analytical techniques for EBC analysis.
American Psychological Association (APA)
Liang, Yan& Yeligar, Samantha M.& Brown, Lou Ann S.. 2012. Exhaled Breath Condensate : A Promising Source for Biomarkers of Lung Disease. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-455412
Modern Language Association (MLA)
Liang, Yan…[et al.]. Exhaled Breath Condensate : A Promising Source for Biomarkers of Lung Disease. The Scientific World Journal No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-455412
American Medical Association (AMA)
Liang, Yan& Yeligar, Samantha M.& Brown, Lou Ann S.. Exhaled Breath Condensate : A Promising Source for Biomarkers of Lung Disease. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-455412
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455412