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Antibiotic Prophylaxis for Children with Primary Vesicoureteral Reflux : Where Do We Stand Today?
Joint Authors
Levtchenko, Elena
Bogaert, Guy
Costers, Michiel
Van Damme-Lombaerts, Rita
Source
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-07-29
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The main goal of the management of vesicoureteral reflux (VUR) is prevention of recurrent urinary tract infections (UTIs), and thereby prevention of renal parenchymal damage possibly ensuing from these infections.
Long-term antibiotic prophylaxis is common practice in the management of children with VUR, as recommended in 1997 in the guidelines of the American Urological Association.
We performed a systematic review to ascertain whether antibiotics can be safely discontinued in children with VUR and whether prophylaxis is effective in the prevention of recurrent UTIs and renal damage in these patients.
Several uncontrolled studies indicate that antibiotic prophylaxis can be discontinued in a subset of patients, that is, school-aged children with low-grade VUR, normal voiding patterns, kidneys without hydronephrosis or scars, and normal anatomy of the urogenital system.
Furthermore, a few recent randomized controlled trials suggest that antibiotic prophylaxis offers no advantage over intermittent antibiotic therapy of UTIs in terms of prevention of recurrent UTIs or new renal damage.
American Psychological Association (APA)
Costers, Michiel& Van Damme-Lombaerts, Rita& Levtchenko, Elena& Bogaert, Guy. 2008. Antibiotic Prophylaxis for Children with Primary Vesicoureteral Reflux : Where Do We Stand Today?. Advances in Urology،Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-455429
Modern Language Association (MLA)
Costers, Michiel…[et al.]. Antibiotic Prophylaxis for Children with Primary Vesicoureteral Reflux : Where Do We Stand Today?. Advances in Urology No. 2008 (2008), pp.1-5.
https://search.emarefa.net/detail/BIM-455429
American Medical Association (AMA)
Costers, Michiel& Van Damme-Lombaerts, Rita& Levtchenko, Elena& Bogaert, Guy. Antibiotic Prophylaxis for Children with Primary Vesicoureteral Reflux : Where Do We Stand Today?. Advances in Urology. 2008. Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-455429
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455429