Cell Death and Inflammatory Bowel Diseases : Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium
Joint Authors
de Souza, Heitor S.
Bernardazzi, Claudio
Nunes, Tiago
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-13
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Cell death mechanisms have been associated with the development of inflammatory bowel diseases in humans and mice.
Recent studies suggested that a complex crosstalk between autophagy/apoptosis, microbe sensing, and enhanced endoplasmic reticulum stress in the epithelium could play a critical role in these diseases.
In addition, necroptosis, a relatively novel programmed necrosis-like pathway associated with TNF receptor activation, seems to be also present in the pathogenesis of Crohn’s disease and in specific animal models for intestinal inflammation.
This review attempts to cover new data related to cell death mechanisms and inflammatory bowel diseases.
American Psychological Association (APA)
Nunes, Tiago& Bernardazzi, Claudio& de Souza, Heitor S.. 2014. Cell Death and Inflammatory Bowel Diseases : Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium. BioMed Research International،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-455502
Modern Language Association (MLA)
Nunes, Tiago…[et al.]. Cell Death and Inflammatory Bowel Diseases : Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium. BioMed Research International No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-455502
American Medical Association (AMA)
Nunes, Tiago& Bernardazzi, Claudio& de Souza, Heitor S.. Cell Death and Inflammatory Bowel Diseases : Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-455502
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455502