Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of Pteleopsis hylodendron (Combretaceae)
Joint Authors
Koanga Mogtomo, Martin Luther
Amvam Zollo, Paul Henri
Mouokeu, Raymond Simplice
Ngono Ngane, Rosalie Annie
Kuiate, Jules-Roger
Mokale Kognou, Aristide Laurel
Tchinda Tiabou, Alembert
Biyiti, Lucie
Source
Chemotherapy Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Pteleopsis hylodendron (Combretaceae) is used in Cameroon and West Africa folk medicine for the treatment of various microbial infections (measles, chickenpox, and sexually transmitted diseases).
The antibacterial properties of the methanolic extract and fractions from stem bark of Pteleopsis hylodendron were tested against three Gram-positive bacteria and eight Gram-negative bacteria using Agar-well diffusion and Broth microdilution methods.
Antioxidant activities of the crude extract and fractions were investigated by DPPH radical scavenging activity and β-carotene-linoleic acid assays.
The methanolic extract and some fractions exhibited antibacterial activities that varied between the bacterial species (ID = 0.00–25.00 mm; MIC = 781–12500 μg/mL and 0.24–1000 μg/mL).
The activity of the crude extract is, however, very weak compared to the reference antibiotics (MIC = 0.125–128 μg/mL).
Two fractions (FE and FF) showed significant activity (MIC = 0.97 μg/mL) while S.
aureus ATCC 25922 was almost resistant to all the tested fractions.
In addition, the crude extract and some fractions showed good antioxidant potential with inhibition values ranging from 17.53 to 98.79%.
These results provide promising baseline information for the potential use of this plant as well as some of the fractions in the treatment of infectious diseases and oxidative stress.
American Psychological Association (APA)
Mokale Kognou, Aristide Laurel& Ngono Ngane, Rosalie Annie& Kuiate, Jules-Roger& Koanga Mogtomo, Martin Luther& Tchinda Tiabou, Alembert& Mouokeu, Raymond Simplice…[et al.]. 2011. Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of Pteleopsis hylodendron (Combretaceae). Chemotherapy Research and Practice،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-455531
Modern Language Association (MLA)
Mokale Kognou, Aristide Laurel…[et al.]. Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of Pteleopsis hylodendron (Combretaceae). Chemotherapy Research and Practice No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-455531
American Medical Association (AMA)
Mokale Kognou, Aristide Laurel& Ngono Ngane, Rosalie Annie& Kuiate, Jules-Roger& Koanga Mogtomo, Martin Luther& Tchinda Tiabou, Alembert& Mouokeu, Raymond Simplice…[et al.]. Antibacterial and Antioxidant Properties of the Methanolic Extract of the Stem Bark of Pteleopsis hylodendron (Combretaceae). Chemotherapy Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-455531
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455531