Comparative Genotoxicity of Cadmium and Lead in Earthworm Coelomocytes
Joint Authors
Muangphra, Ptumporn
Gooneratne, Ravi
Source
Applied and Environmental Soil Science
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Earth Science , Water and Environment
Abstract EN
To determine genotoxicity to coelomocytes, Pheretima peguana earthworms were exposed in filter paper studies to cadmium (Cd) and lead (Pb) for 48 h, at concentrations less than the LC10—Cd: 0.09, 0.19, 0.38, 0.75, and 1.50 μg cm−2; Pb: 1.65, 3.29, 6.58, 13.16, and 26.32 μg cm−2.
For Cd at 0.75 μg cm−2, in the micronucleus test (detects chromosomal aberrations), significant increases (P<.05) in micronuclei and binucleate cells were observed, and in the comet assay (detects DNA single-strand breaks), tail DNA% was significantly increased.
Lead was less toxic with minimal effects on DNA, but the binucleates were significantly increased by Pb at 3.29 μg cm−2.
This study shows that Cd is more acutely toxic and sublethally genotoxic than Pb to P.
peguana.
Cadmium caused chromosomal aberrations and DNA single-strand breaks at 45% of the LC10 concentration.
Lead, in contrast, did not induce DNA damage but caused cytokinesis defects.
American Psychological Association (APA)
Muangphra, Ptumporn& Gooneratne, Ravi. 2011. Comparative Genotoxicity of Cadmium and Lead in Earthworm Coelomocytes. Applied and Environmental Soil Science،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-455541
Modern Language Association (MLA)
Muangphra, Ptumporn& Gooneratne, Ravi. Comparative Genotoxicity of Cadmium and Lead in Earthworm Coelomocytes. Applied and Environmental Soil Science No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-455541
American Medical Association (AMA)
Muangphra, Ptumporn& Gooneratne, Ravi. Comparative Genotoxicity of Cadmium and Lead in Earthworm Coelomocytes. Applied and Environmental Soil Science. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-455541
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455541