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Effect of Dietary Supplements in Reducing Probability of Death for Uremic Crises in Dogs Affected by Chronic Kidney Disease (Masked RCCT)
Joint Authors
Zatelli, Andrea
Pierantozzi, Marco
Bigliati, Mauro
Zini, Eric
D'Ippolito, Paola
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Chitosan and alkalinizing agents can decrease morbidity and mortality in humans with chronic kidney disease (CKD).
Whether this holds true in dog is not known.
Objective of the study was to determine whether a commercial dietary supplement containing chitosan, phosphate binders, and alkalinizing agents (Renal), compared to placebo, reduces mortality rate due to uremic crises in dogs with spontaneous CKD, fed a renal diet (RD).
A masked RCCT was performed including 31 azotemic dogs with spontaneous CKD.
Dogs enrolled in the study were randomly allocated to receive RD plus placebo (group A; 15 dogs) or RD plus Renal (group B; 16 dogs).
During a first 4-week period, all dogs were fed an RD and then randomized and clinically evaluated up to 44 weeks.
The effects of dietary supplements on mortality rate due to uremic crises were assessed.
At 44 weeks, compared to group A, dogs in group B had approximately 50% lower mortality rate due to uremic crises (P=0.015).
Dietary supplementation with chitosan, phosphate binders, and alkalinizing agents, along with an RD, is beneficial in reducing mortality rate in dogs with spontaneous CKD.
American Psychological Association (APA)
Zatelli, Andrea& Pierantozzi, Marco& D'Ippolito, Paola& Bigliati, Mauro& Zini, Eric. 2012. Effect of Dietary Supplements in Reducing Probability of Death for Uremic Crises in Dogs Affected by Chronic Kidney Disease (Masked RCCT). The Scientific World Journal،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-455558
Modern Language Association (MLA)
Zatelli, Andrea…[et al.]. Effect of Dietary Supplements in Reducing Probability of Death for Uremic Crises in Dogs Affected by Chronic Kidney Disease (Masked RCCT). The Scientific World Journal No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-455558
American Medical Association (AMA)
Zatelli, Andrea& Pierantozzi, Marco& D'Ippolito, Paola& Bigliati, Mauro& Zini, Eric. Effect of Dietary Supplements in Reducing Probability of Death for Uremic Crises in Dogs Affected by Chronic Kidney Disease (Masked RCCT). The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-455558
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-455558